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Saiko-agents, herbal medicines, Kamishoyosan and Saikokeishikankyoto, regulate the plasma interferon-γ (IFN-γ) concentration in the improvement of undefined symptoms in depressed postmenopausal women
https://aino.repo.nii.ac.jp/records/329
https://aino.repo.nii.ac.jp/records/329be1ae13a-dce7-412a-b625-4c463298a8b0
| 名前 / ファイル | ライセンス | アクション |
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KJ00005223105.pdf (772.9 kB)
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| Item type | [ELS]紀要論文 / Departmental Bulletin Paper(1) | |||||||||||
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| 公開日 | 2019-03-27 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Saiko-agents, herbal medicines, Kamishoyosan and Saikokeishikankyoto, regulate the plasma interferon-γ (IFN-γ) concentration in the improvement of undefined symptoms in depressed postmenopausal women | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 主題 | saiko-agent, Saikokeishikankyoto, Kamishoyosan, interferon-γ, undefined symptom, postmenopausal women | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| 著者 |
Ushiroyama, Takahisa
× Ushiroyama, Takahisa
× Sakuma, Kou
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| 抄録(英) | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Aims: To investigate the effects of herbal medicines, saiko-agents (Saikokeishikankyoto and Kamishoyosan), on the improvement of a depressed mood and on plasma interferon-γ (IFN-γ) concentrations in comparison with those of antidepressants in peri- and postmenopausal women. Methods: Sixty-seven patients complaining of menopausal symptoms including a depressed mood who were diagnosed with mood disorder based on DSM-IV were recruited and divided into two groups (the saiko-agent group was selected on the basis of SHO: 28 cases, antidepressant group: 39 cases), and plasma IFN-γ concentrations were analyzed before and after 1, 2, and 3 months of treatment. Results: There were no significant differences in the decreasing rate of either the climacteric or Hamilton depression score after treatment between the two groups. Plasma IFN-γ concentrations decreased significantly more in the saiko-agent group (-14.3±3.5%) than in the antidepressants group (3.5±1.8%) after 3 months of treatment. A relationship between the rate of the decrease in the climacteric score and plasma IFN-γ (R=0.498, P=0.0056) concentration was observed on treatment with saiko-agents. Conclusion: Saiko-agents, herbal medicines, reduced the plasma IFN-γ concentration related to the improvement of a depressed mood during the treatment in postmenopausal women with undefined symptoms. The findings of the present study indicate that saiko-agents appear to have the potential to decrease morbidity by the alleviation of stress reactions. | |||||||||||
| 言語 | en | |||||||||||
| 書誌情報 |
en : AINO JOURNAL 巻 6, 号 1, p. 11-17, ページ数 7, 発行日 2008-03-31 |
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| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 1348480X | |||||||||||
