{"created":"2023-05-15T12:16:41.120426+00:00","id":329,"links":{},"metadata":{"_buckets":{"deposit":"7c3af8d4-fb45-429b-8e1e-547b73e52088"},"_deposit":{"created_by":4,"id":"329","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"329"},"status":"published"},"_oai":{"id":"oai:aino.repo.nii.ac.jp:00000329","sets":["7:38"]},"author_link":["2320","1097"],"control_number":"329","item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicNumberOfPages":"7","bibliographicPageEnd":"17","bibliographicPageStart":"11","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"AINO JOURNAL","bibliographic_titleLang":"en"}]}]},"item_3_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Aims: To investigate the effects of herbal medicines, saiko-agents (Saikokeishikankyoto and Kamishoyosan), on the improvement of a depressed mood and on plasma interferon-γ (IFN-γ) concentrations in comparison with those of antidepressants in peri- and postmenopausal women. Methods: Sixty-seven patients complaining of menopausal symptoms including a depressed mood who were diagnosed with mood disorder based on DSM-IV were recruited and divided into two groups (the saiko-agent group was selected on the basis of SHO: 28 cases, antidepressant group: 39 cases), and plasma IFN-γ concentrations were analyzed before and after 1, 2, and 3 months of treatment. Results: There were no significant differences in the decreasing rate of either the climacteric or Hamilton depression score after treatment between the two groups. Plasma IFN-γ concentrations decreased significantly more in the saiko-agent group (-14.3±3.5%) than in the antidepressants group (3.5±1.8%) after 3 months of treatment. A relationship between the rate of the decrease in the climacteric score and plasma IFN-γ (R=0.498, P=0.0056) concentration was observed on treatment with saiko-agents. Conclusion: Saiko-agents, herbal medicines, reduced the plasma IFN-γ concentration related to the improvement of a depressed mood during the treatment in postmenopausal women with undefined symptoms. The findings of the present study indicate that saiko-agents appear to have the potential to decrease morbidity by the alleviation of stress reactions.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1348480X","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Ushiroyama, Takahisa","creatorNameLang":"en"}],"familyNames":[{"familyName":"Ushiroyama","familyNameLang":"en"}],"givenNames":[{"givenName":"Takahisa","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2320","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakuma, Kou","creatorNameLang":"en"}],"familyNames":[{"familyName":"Sakuma","familyNameLang":"en"}],"givenNames":[{"givenName":"Kou","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1097","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-03-27"}],"displaytype":"detail","filename":"KJ00005223105.pdf","filesize":[{"value":"772.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00005223105.pdf","url":"https://aino.repo.nii.ac.jp/record/329/files/KJ00005223105.pdf"},"version_id":"5752fb6a-f650-4a7a-86ab-a305d068c12a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"saiko-agent","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Saikokeishikankyoto","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Kamishoyosan","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"interferon-γ","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"undefined symptom","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"postmenopausal women","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Saiko-agents, herbal medicines, Kamishoyosan and Saikokeishikankyoto, regulate the plasma interferon-γ (IFN-γ) concentration in the improvement of undefined symptoms in depressed postmenopausal women","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Saiko-agents, herbal medicines, Kamishoyosan and Saikokeishikankyoto, regulate the plasma interferon-γ (IFN-γ) concentration in the improvement of undefined symptoms in depressed postmenopausal women","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["38"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-03-27"},"publish_date":"2019-03-27","publish_status":"0","recid":"329","relation_version_is_last":true,"title":["Saiko-agents, herbal medicines, Kamishoyosan and Saikokeishikankyoto, regulate the plasma interferon-γ (IFN-γ) concentration in the improvement of undefined symptoms in depressed postmenopausal women"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2025-09-11T06:10:27.774165+00:00"}