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Molecular mechanism of angiogenesis
https://aino.repo.nii.ac.jp/records/423
https://aino.repo.nii.ac.jp/records/4235892c097-e2e5-4f77-8335-bbfe0a1229e8
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00010289059.pdf (414.6 kB)
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| Item type | [ELS]紀要論文 / Departmental Bulletin Paper(1) | |||||||||
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| 公開日 | 2019-03-27 | |||||||||
| タイトル | ||||||||||
| タイトル | Molecular mechanism of angiogenesis | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題 | Sprouting angiogenesis, VEGF signal, Lmo2 complex | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 著者 |
Yamada, Yoshihiro
× Yamada, Yoshihiro
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| 抄録(英) | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Angiogenesis is one of the chief events both in development and postnatal pathological conditions. Recent extensive studies revealed the key signaling and transcriptional regulators of sprouting angiogenesis. Sprouting angiogenesis is a multistep process composed of endothelial loosening, endothelial cell migration, stalk elongation, anastomosis, and stabilization. Although the initial process of sprouting is triggered by soluble proangiogenic factors such as VEGF and FGF, the rather complicated subsequent step recruits many signaling and adhesion molecules which are pivotal players in autonomous and conditional specification in development. There is a marked similarity at the molecular level between embryogenic and postnatal angiogenesis. By its physiological constraint, endothelium differentiation is closely linked with blood cell specification. Many transcription factors with a major role in hematopoietic stem cell generation are also involved in angiogenesis. | |||||||||
| 言語 | en | |||||||||
| 書誌情報 |
en : AINO JOURNAL 巻 14, 号 1, p. 27-32, ページ数 6, 発行日 2016-03-31 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 1348480X | |||||||||
