| Item type |
[ELS]紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2019-03-27 |
| タイトル |
|
|
タイトル |
Choroid plexus -with special reference to neuroprotective function- |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
trophic function, nerve protection, transplantation, culture, in situ hybridization |
| 資源タイプ |
|
|
資源タイプ |
departmental bulletin paper |
| 雑誌書誌ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11877461 |
| 著者 |
Homma, Tamami
Nakano, Norihiko
Yamada, Yoshihiro
Ide, Chizuka
|
| 抄録(英) |
|
|
内容記述 |
Choroid plexus (CT) produces the cerebrospinal fluid (CSF) that fills the ventricles and subarachnoidal space, and infiltrates the intercellular spaces of CNS parenchyma. CP transplantation enhances axonal outgrowth in the spinal cord lesion. Cultured choroid plexus epithelial cells (CPECs) secret neurotrophic factors into the medium. CP undergoes cytological changes in diseases such as Alzheimer and Huntingon's disease. The ischemia-injured infraction due to middle cerebral artery occlusion is suppressed by transplantation of CPECs into the CSF in the rat. Allo- or xenotransplantation of encapsulated CP has been studied for the treatment of experimental Huntington's disease. CP can be regarded as the neurotrophic center of the CNS, regulating and maintaining the normal brain function via CSF. |
|
言語 |
en |
| 書誌情報 |
en : AINO JOURNAL
巻 10,
号 1,
p. 33-43,
ページ数 11,
発行日 2012-03-31
|
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
1348480X |
KJ00008182459.pdf (1.6 MB)
