| Item type |
[ELS]紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2019-03-27 |
| タイトル |
|
|
タイトル |
Interstitial pneumonia and de-novo onset of asthma induced by leuprorelin acetate for prostate cancer |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
leuprorelin acetate, interstitial pneumonia, chemokine receptor, Th 1/Th 2 balance, bronchial asthma, prostate cancer |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者 |
Yamasaki, Hidetomo
Nakajima, Hideto
Tanaka, Toshifumi
Ohsawa, Nakaaki
|
| 抄録(英) |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We describe herein the first report of side effects induced by leuprorelin acetate (LA) administration. A 70-year-old man, with idiopathic pulmonary fibrosis (IPF), vasospastic angina, diabetes mellitus type 2, and arteriosclerosis obliterans was suffering from prostate cancer. LA administration (drug-) induced interstitial pneumonia based on IPF and the de-novo onset of bronchial asthma, both of which are thought to be Th 2-related diseases. Using 3-color flow cytometry, we analyzed the chemokine receptors CD4+CXCR3+/CD3+ and CD4+CCR4+/CD3+, and found that the CXCR3/CCR4 ratio changed in the Th 2 pattern. It is important to be careful with LA administration, especially for underlying Th 2-related diseases, and clinicians should fully understand the possibilities of LA-inducing de-novo Th 1/Th 2-driven autoimmune diseases. |
|
言語 |
en |
| 書誌情報 |
en : AINO JOURNAL
巻 5,
号 1,
p. 73-76,
ページ数 4,
発行日 2006
|
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
1348480X |
KJ00005223091.pdf (554.6 kB)
