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  1. AINO JOURNAL
  2. vol.4

An overview of caveolins and their distributions in the endocrine system

https://aino.repo.nii.ac.jp/records/293
https://aino.repo.nii.ac.jp/records/293
9fa9cdd8-3ce8-465f-b008-9c0e8572d2d4
名前 / ファイル ライセンス アクション
KJ00004437028.pdf KJ00004437028.pdf (1.1 MB)
Item type [ELS]紀要論文 / Departmental Bulletin Paper(1)
公開日 2019-03-27
タイトル
タイトル An overview of caveolins and their distributions in the endocrine system
言語 en
言語
言語 eng
キーワード
主題 caveolin-1, caveolin-3, endocrine system
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
著者 Maeda, Tamaki

× Maeda, Tamaki

en Maeda, Tamaki

ja ISNI

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Hatanaka, Michiyo

× Hatanaka, Michiyo

en Hatanaka, Michiyo

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抄録(英)
内容記述タイプ Abstract
内容記述 Caveolins, the proteins which were found in "little caves" named caveolae more than 50 years ago, have been revealed to work to maintain the form and functions of many kinds of cells. Therefore malfunction of caveolins is related to diseases such as tumors, atherosclerosis, muscular dystrophy, pulmonary disfunction and other diseases. The introduction of caveolin-deficient mice brought new methods to approach the mechanisms of both normal cell function and the onset of these diseases. Although we examined caveolin distribution in human tissue, it has been difficult to establish a relationship between the caveolins and hormone secretion. However, as caveolin-1 has direct functional interactions with insulin receptors, Type II diabetes mellitus has become one subject for caveolin research. In terms of tumorigenesis, there are some reports of overexpression of caveolin-1 and -2 in tumors of the thyroid and parathyroid. Caveolins are proteins which have the potential for much further research, from many points of view.
言語 en
書誌情報 en : AINO JOURNAL

巻 4, 号 1, p. 11-17, ページ数 7, 発行日 2005
ISSN
収録物識別子タイプ PISSN
収録物識別子 1348480X
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