{"created":"2023-05-15T12:17:00.946343+00:00","id":697,"links":{},"metadata":{"_buckets":{"deposit":"05afa990-759f-4720-aba7-dc4fa76b30ce"},"_deposit":{"created_by":8,"id":"697","owners":[8],"pid":{"revision_id":0,"type":"depid","value":"697"},"status":"published"},"_oai":{"id":"oai:aino.repo.nii.ac.jp:00000697","sets":["8:67"]},"author_link":["1227","2543"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"72","bibliographicPageStart":"61","bibliographicVolumeNumber":"28","bibliographic_titles":[{"bibliographic_title":"藍野学院紀要"},{"bibliographic_title":"Bulletin of Aino Gakuin","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"肝機能検査は肝臓の病態について有力な情報を提示する。肝機能検査には多くの検査項目があり,一見したところ統一が無いように見えるが,異常値が発現するメカニズムからその原理を見ると,大きく3つに分類できる。1つはAST,ALT,LDHなどの細胞質内物質であり,これらは肝臓の破壊過程をリアルタイムで定量的に反映する。2つ目はAlb,ChEなど肝細胞内で合成され,血中に分泌された物質である。これらの血中レベルは肝臓が健常な時は正常値を保つが,肝硬変や肝細胞がんなど,合成の場である肝細胞数が減少すると,血中での値は低下する。3番目はAlP,γGTP等の胆道系酵素であり,胆道系を流れる胆汁のうっ滞で異常を示す。肝臓病の機能的病態は,これら3つの要素の解析により,全体的な把握できるのである。(著者抄録)","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"藍野学院"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0918-6263","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"黒澤, 和平","creatorNameLang":"ja"},{"creatorName":"クロサワ, カズヘイ","creatorNameLang":"ja-Kana"},{"creatorName":"Kazuhei, Kurosawa","creatorNameLang":"en"}],"familyNames":[{"familyName":"黒澤","familyNameLang":"ja"},{"familyName":"クロサワ","familyNameLang":"ja-Kana"},{"familyName":"Kazuhei","familyNameLang":"en"}],"givenNames":[{"givenName":"和平","givenNameLang":"ja"},{"givenName":"カズヘイ","givenNameLang":"ja-Kana"},{"givenName":"Kurosawa","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2543","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KUROSAWA, Kazuhei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1227","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-04-27"}],"displaytype":"detail","filename":"黒澤：肝機能検査の原理とその生化学的背景.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"黒澤：肝機能検査の原理とその生化学的背景","url":"https://aino.repo.nii.ac.jp/record/697/files/黒澤：肝機能検査の原理とその生化学的背景.pdf"},"version_id":"1325417f-8032-4ca6-9440-095bf04b61c7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"肝機能検査","subitem_subject_scheme":"Other"},{"subitem_subject":"生化学的背景","subitem_subject_scheme":"Other"},{"subitem_subject":"Liver Function Test ｜Biochemical Background","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"肝機能検査の原理とその生化学的背景","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肝機能検査の原理とその生化学的背景"},{"subitem_title":"Mechanism of Liver Function Tests and their Biochemical Background","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"8","path":["67"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-06-29"},"publish_date":"2022-06-29","publish_status":"0","recid":"697","relation_version_is_last":true,"title":["肝機能検査の原理とその生化学的背景"],"weko_creator_id":"8","weko_shared_id":8},"updated":"2024-10-11T09:43:03.684842+00:00"}