| Item type |
[ELS]紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2019-03-27 |
| タイトル |
|
|
タイトル |
An autopsy case of Pick's disease and mini-review of the literature |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Pick's disease, tauopathy, autopsy |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者 |
Maeda, Tamaki
Tsutsumi, Shigetoshi
Mori, Hiroshi
|
| 抄録(英) |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The authors report a case of a Pick's disease which was at first diagnosed as residual schizophrenia. The patient received the diagnosis of Pick's disease three years later based on a CT scan which showed cerebral atrophy, and died from pneumonia about ten years after the onset. Autopsy revealed cerebral atrophy in the frontal and temporal lobes and histologically many Pick bodies were observed in the cortex and hippocampus. Pick bodies were examined immunohistochemically and ultrastructually. The necessity of Pick bodies to diagnose Pick's disease has been a source of contention since this disease was first named, so Pick's disease continues to be investigated by new methods. From image-based method of diagnosis, new clinicopathological diagnostic criteria for frontotemporal dementia was proposed. Additionally, Pick's disease is a member of the classification of diseases known as tauopathy, based upon the concept of abnormal protein accumulation in the brain. The recent classification should be referred to make accurate diagnosis to this kind of diseases. |
|
言語 |
en |
| 書誌情報 |
en : AINO JOURNAL
巻 3,
号 1,
p. 81-85,
ページ数 5,
発行日 2004
|
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
1348480X |
KJ00004291419.pdf (1.2 MB)
